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David J Silverman Selected Research

Rocky Mountain Spotted Fever (Sao Paulo Typhus)

10/2005Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response.
8/2005Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB.
5/2004NF-kappaB activation suppresses host cell apoptosis during Rickettsia rickettsii infection via regulatory effects on intracellular localization or levels of apoptogenic and anti-apoptotic proteins.
7/2003Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity.
6/2003Rickettsia rickettsii infection in the pine vole, Microtus pinetorum: kinetics of infection and quantitation of antioxidant enzyme gene expression by RT-PCR.
8/2002Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression.

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David J Silverman Research Topics

Disease

10Infections
07/2007 - 08/2002
6Rocky Mountain Spotted Fever (Sao Paulo Typhus)
10/2005 - 08/2002
2Spotted Fever Group Rickettsiosis (Rickettsialpox)
09/2006 - 12/2005
1Fever (Fevers)
11/2011
1Bartonella Infections (Bartonellosis)
02/2008
1Inflammation (Inflammations)
08/2005
1Boutonneuse Fever (Mediterranean Spotted Fever)
06/2004
1B-Cell Lymphoma (Lymphoma, B Cell)
05/2004

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
02/2008 - 08/2002
6EnzymesIBA
09/2006 - 08/2002
5NF-kappa B (NF-kB)IBA
07/2007 - 07/2003
5AntioxidantsIBA
09/2006 - 08/2002
2Phosphotransferases (Kinase)IBA
07/2007 - 10/2005
2Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
09/2006 - 12/2005
2CytokinesIBA
09/2006 - 10/2005
2Messenger RNA (mRNA)IBA
09/2006 - 08/2002
2Protein Isoforms (Isoforms)IBA
09/2006 - 12/2005
2ChemokinesIBA
10/2005 - 08/2005
2Transcription Factors (Transcription Factor)IBA
08/2005 - 07/2003
2Caspase 3 (Caspase-3)IBA
05/2004 - 07/2003
1Anti-Bacterial Agents (Antibiotics)IBA
11/2011
1VaccinesIBA
11/2011
1AntigensIBA
02/2008
1DNA (Deoxyribonucleic Acid)IBA
07/2007
1ProstaglandinsIBA
09/2006
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
09/2006
1IsoenzymesIBA
12/2005
1Monocyte Chemoattractant ProteinsIBA
10/2005
1Phospholipases (Phospholipase)IBA
10/2005
1MitogensIBA
10/2005
1SB 203580IBA
10/2005
1InterleukinsIBA
10/2005
1Cytochalasin DIBA
10/2005
1Protein Kinases (Protein Kinase)IBA
10/2005
1Formaldehyde (Formol)FDA Link
10/2005
1Chemotactic FactorsIBA
10/2005
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2005
1Interleukin-8 (Interleukin 8)IBA
08/2005
1Glutathione (Reduced Glutathione)IBA
06/2004
1Oxidants (Oxidizing Agents)IBA
06/2004
1Thioctic Acid (Lipoic Acid)IBA
06/2004
1Superoxides (Superoxide)IBA
06/2004
1Apoptosis Regulatory ProteinsIBA
05/2004
1Effector CaspasesIBA
07/2003
1CaspasesIBA
07/2003
1Cycloheximide (Cicloheximide)IBA
08/2002
1Heme Oxygenase-1IBA
08/2002
1Protein Synthesis InhibitorsIBA
08/2002